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Alfonzo is a character from The Legend of Zelda: Spirit Tracks who got popular among Miiverse users after one of Sakurai's Pic of the Day posts. Alfonzo became a meme on Miiverse when users decided to use the caption from the post: "Leave it to me!" Alfonzo has recently caught on even more to the point of becoming a Miiverse phenomenon, only rivaled by Hatty and Bigley.
The meme grew in popularity once again on August 16, 2014, when a Miiverse user changed his name to Alfonzo (User) and started overusing the meme. The meme would be used over and over again throughout the year. The meme was forgotten after the release of Super Smash Bros for Wii U, after the Pic of the Day series ended.
In 2014 the Alfonzo user returned to revive the dead meme on March 2015, the meme lasted a few days, but soon became forgotten once again.